Fourteen entries competed in the national final on 19 February 2022 and "Guilty Pleasure" performed by Mia Dimšić was selected as the winner following the combination of votes from ten regional juries and a public televote.

Since 2018, the Croatian entries failed to qualify from the semi-finals; the last time Croatia competed in the final was in 2017 with the song "My Friend" performed by Jacques Houdek.

The competition consisted of fourteen entries competing in one final on 19 February 2022 at the Marino Cvetković Sports Hall in Opatija, hosted by Duško Ćurlić, Elizabeta Brodić [hr] and 2018 Croatian Eurovision entrant Franka Batelić.

[5] On 27 October 2021, HRT opened a submission period where artists and composers were able to submit their entries to the broadcaster with the deadline on 25 November 2021, which was later extended until 12 December 2021.

[8] The running order of the final was determined during the HRT 1 show Kod Nas Doma, hosted by Branimir Mihaljević [hr] and Barbara Kolar.

[11] The winner, "Guilty Pleasure" performed by Mia Dimšić, was determined by a 50/50 combination of votes from ten regional juries and a public televote.

[13][14] In late March, Mia Dimšić filmed the music video for "Guilty Pleasure" in Osijek, which was directed by Artem Dushkin and the company Lumiere Productions.

[18] Mia Dimšić made several appearances across Europe to specifically promote "Guilty Pleasure" as the Croatian Eurovision entry.

[20] On 9 April, Dimšić performed during the Eurovision in Concert event which was held at the AFAS Live venue in Amsterdam, Netherlands and hosted by Cornald Maas and Edsilia Rombley.

[21] On 16 April, Dimšić performed during the PrePartyES 2022 event which was held at the Sala La Riviera venue in Madrid, Spain and hosted by Ruth Lorenzo.

[22] In addition to her international appearances, Mia Dimšić performed during the Adriatic PreParty which was held online and organised by Hrvatski Eurovizijski Klub.

[28] The Croatian performance featured Mia Dimšić in a pink silk dress and black boots designed by Ivan Tandarić and Aleksandar Šekuljica.

The stage colours were predominantly pink and blue and Dimšić performed the bridge and final chorus of "Guilty Pleasure" in the Croatian language.