[6] Tree's Broadway credits include Bright Honor (1936), Clear All Wires (1932), The Merchant of Venice (1930), Holiday (1928), The Marquise (1927), and The Triumphant Bachelor (1927).

Tree attracted attention as a feminine menace on the screen as the hairdresser-spy, Hilda Kleinhauer, in the Warner Bros. drama Confessions of a Nazi Spy (1939) starring Edward G. Robinson, which won the National Board of Review Award for Best Film – English Language.

She was signed by RKO to portray the important role as Elizabeth Edwards, Mary Todd's sister, in Abe Lincoln in Illinois (1940) starring Raymond Massey.

Tree also appeared as Aunt Martha Dale in a teleplay of the live television anthology series The Silver Theatre (1950), which was titled Minor Incident.

On November 4, 1956, an article written by Uris about English singing with good diction and its aiding a singer to clarify words for the listener was published in the New York Times.

[citation needed] Dorothy Tree Uris died at age 85 of heart failure at the Actors Fund of America Nursing Home in Englewood, New Jersey.