It is located in the inner city at the junction of Ruhrallee (B54) and Märkischen Straße, near the Stadthaus, a municipal office building.

Line S4 runs in the east–west direction from Unna to Dortmund-Luetgendortmund on above ground tracks through the station.

In addition, bus route 444 operated by the municipal bus company, Dortmunder Stadtwerke (DSW21), stops in front of the station, connecting to Dortmund Hauptbahnhof and the Hohensyburg Casino at Syburg each hour.

In December 2011, line S4 was converted to operation by class 422 electric multiple units.

[6] Dortmund Stadthaus station is served by Rhine-Ruhr S-Bahn line S 4 at 20-minute intervals.