During the War of the Pacific, the hospital was occupied by the Chilean Army from February 20, 1881, to December 29, 1883, with only children being able to receive attention.

[2] On October 5, 1885, sixth-year medical student Daniel Alcides Carrión succumbed to his condition at the hospital.

[4] Carrión is buried in a mausoleum on the premises of the hospital,[5] and was declared a national hero on October 7, 1991.

[6] The hospice system at the end of the 19th century varied in the following way; outpatient care in 1891, first clinical laboratory in 1900.

[2] For fifty years, inspectors of the Charity of Lima was in charge of managing the hospital, who were chosen from among the members of the institution; Starting in 1921, the first medical director was appointed, who was Dr. Leonidas Avendaño.