It was built in 1907 as the largest and busiest on the Atlantic Coast Line Railroad between Montgomery, Alabama, and Thomasville, Georgia and replaced a former freight depot.

In 1971, Amtrak took over passenger rail service in the United States and Dothan station was served by the Floridian until 1979.

The first story's hipped roof wraps around the entire building, and has deep eaves supported by large brackets.

All windows are two-over-two sashes with heavy granite sills and lintels.

This article about a property in Alabama on the National Register of Historic Places is a stub.