[25] In 2011, Wigdor represented Nafissatou Diallo, a housekeeper attacked in the Sofitel Hotel by Dominique Strauss-Kahn, the former head of the International Monetary Fund.

[8] Three of Wigdor's clients, Wedil David,[33] Kaja Sokola,[34] and Dominique Huett,[35] filed civil lawsuits alleging that they were sexually assaulted by Weinstein after he invited them to meet with him to discuss potential acting roles.

[6] The lawsuit accused the NFL of conducting sham interviews with Black and minority head coach candidates in order to show compliance with the Rooney Rule.

[56] On July 1, 2020, it was reported that Wigdor represented the victim in a sexual misconduct case that led to the termination of Fox News host Ed Henry.

Fox News on-air talent Sean Hannity, Tucker Carlson, Howard Kurtz and Gianno Caldwell were also accused of sexual harassment in the lawsuit.

[60] Wigdor told the press that the decision was "by no means a reflection on whether then-Senator Biden sexually assaulted Ms. Reade" and that his views on the allegations had not changed.

[63] Two years later, Wigdor sued Uber on behalf of the victim, accusing the company's top executives of unlawfully obtaining and sharing her private medical records.

[67] The case prompted widespread controversy surrounding the credibility of the awards[68][69] and reportedly caused Taylor Swift to cancel a surprise performance at the ceremony in solidary with Dugan.

[72] Other celebrity musicians who have publicly backed Dugan amid the controversy include Nicki Minaj,[73] Sheryl Crow,[74] Chuck D,[75][76] and Tyler, the Creator.

[77] Later that year, The Weeknd accused the Recording Academy of ongoing corruption after his chart-topping studio album After Hours was shut out of the nominations for the 63rd Annual Grammy Awards.

[78] On May 5, 2020, multiple media outlets reported that Wigdor represented several women in an investigation led by the New York Attorney General's office into sexual harassment allegations at NBC News, including Megyn Kelly and Linda Vester.

[79][80] Wigdor represented five longtime female news anchors at NY1 in an age and gender discrimination lawsuit against Charter Communications, the station's parent company.

[85] Crawford claimed that investigators dismissed her attempts to come forward with relevant information about the conduct in question, followed by Goldman Sachs terminating her employment in an apparent effort to silence her.

[87] High-profile lawyer Roberta Kaplan was criticized for her role defending Goldman Sachs in the case despite her work as the co-founder of the Time's Up Legal Defense Fund.

[88][89] After Kaplan sought to move the case from federal court into private arbitration Wigdor said it was "disappointing that she would agree to take such an anti-#MeToo position on Goldman's behalf.

[95] In January 2024, Douglas Wigdor filed a lawsuit against James Dolan, Harvey Weinstein, and related corporations alleging sex trafficking and sexual assault.

[97] Law360 named Wigdor to its Titans of the Plaintiffs Bar list in 2019, calling him "among the most prominent litigators in the current nationwide reckoning on sexual misconduct".

[104] Wigdor was awarded a Band 1 ranking by Chambers and Partners[105] and has been named a Top 100 attorney in the New York metro area by Super Lawyers from 2007-09 and 2013-24.