Previously sharing a campus with the television station KLCS on West Temple Street, the school relocated to the Edward R. Roybal Learning Center beginning of the 2022–2023 year.

[6] After founding the Los Angeles Center for Enriched Studies in 1977, David Peha founded Downtown Business Magnet in 1981 as a component of LAUSD's expanding voluntary integration program specializing in bushiness training.

[7] The school's first class consisted of 55 sophomores from different neighborhoods around Downtown Los Angeles.

[10] The magnet program was developed with the Los Angeles Central Library[broken anchor] and the UCLA Graduate School of Education in collaboration with several local business leaders and LAUSD board members.

[16][17] The school participates in sports such as basketball, cross country, softball, tennis, volleyball, and track and field.

[20] For the 2019-2020 school year, DMHS had an enrollment of 1056 students, broken down into 25% freshmen, 27.3% sophomores, 25.4% juniors, and 22.3% seniors.

Since the 2007-2008 school year, Downtown Magnets has placed number one in Local District 4, thanks to the continual growth of its API Its scores are as follows: The aforementioned data is provided by the California Department of Education.