At Karanja Lad, he reached ninth grade, before he was admitted into Hind High School,Amravati, and Fergusson College in Pune.

He did satyagraha to allow untouchables to enter Ambabai Temple, Amravati, which was condemned by the upper castes.

After the death of his father, his mother asked him to conduct traditional activity "Shradhha" with Brahmins.

After the marriage ceremony, when he reached Amravati, his friends convinced Deshmukh to give a party.

An agricultural university bearing his name operates at Akola, i.e. Panjabrao Deshmukh Krishi Vidyapeeth.

He dedicated his talent and energy for the formulation and implementation of the policies that would bring prosperity to agriculture and the agriculturist.

He established the Bharat Krishak Samaj and launched a campaign called Food for Millions in 1955.

The fair was visited by dignitaries across the world, including US President Dwight Eisenhower, Soviet first secretary Nikita Khrushchev, Lord and Lady Mountbatten.

His most predominant case was British Government vs. Azad Hind Sena, in which he assisted Jawaharlal Nehru.