The Dr. H. Huber Block was a historic commercial building in downtown Ottawa, Ohio, United States.

Built in 1882,[1] it was erected for Dr. Hubert Huber, a native of Germany who immigrated to the nearby village of Glandorf in 1853.

Besides maintaining a medical practice in the building, Huber also operated a pharmacy on the first story that continued in operation long after his death; the second floor consisted of residential apartments that he rented out to others, and the third floor was used for nearly a century as a meeting place for the local Knights of Columbus lodge.

[2] In 1980, the Huber Block was listed on the National Register of Historic Places.

[1] It qualified for inclusion because of its well-preserved historic architecture, which was seen as significant in the local community.