Dr. John Glenn House is a historic home located near Jenkinsville, Fairfield County, South Carolina.

It was built about 1845, and is a two-story, five-bay, weatherboarded frame, end-gabled Greek Revival style residence.

It has a double-pile and central-hall plan with a rear shed room.

The front façade features a two-tiered porch in the three central bays with a pedimented gable end.

This article about a property in Fairfield County, South Carolina on the National Register of Historic Places is a stub.