Throughout the television series, Dr. Loveless conceived numerous plots which were always foiled by Secret Service agents James West and Artemus Gordon.

In "The Night of the Bogus Bandits", it is revealed that Loveless' greatest fear is not death, but the fact that once deceased, he cannot continue his plans of revenge against a society which he hates so much.

In the series' first season, his inventions were more practical, anticipating the cathode-ray tube, the airplane, penicillin, automobile ("The Night the Wizard Shook the Earth") and a synthesized LSD-like hallucinogen.

In the second season, the inventions became more fantastic and included a powder that shrank Jim West to one-twelfth his original size, and a device that allowed people to enter paintings.

[1] Perhaps the most phantasmagorical of his methods for avoiding capture was when he and his assistant Antoinette (Phoebe Dorin) escaped West and Gordon by shrinking themselves and flying away on the back of a swan ("The Night of the Raven").

However, they each left such an indelible impression on fans that the 1990 comic book miniseries from Millennium Publications, a sequel to the TV series scripted by Mark Ellis with art by Darryl Banks, included both characters.