Dr. Samuel Perry House is a historic plantation house located near Gupton, Franklin County, North Carolina.

It was built about 1857, and is a two-story, three-bay, four-square Italianate / Greek Revival style frame dwelling.

It was built by noted American carpenter and builder Jacob W. Holt (1811-1880).

[2] It was listed on the National Register of Historic Places in 1975.

This article about a property in Franklin County, North Carolina on the National Register of Historic Places is a stub.