[4] His book Counselling in Male Infertility was published in 1996; he contributed to major newspaper articles and appeared on several current affairs television programmes.
He was the "inspiration" for Anthony Ling, the character in the novel One Life by Rebecca Frayn (Simon & Schuster 2006, ISBN 0-7432-6876-8), after the author herself sought Lee's help for IVF treatment.
He was a visiting professor at the University College London where he collaborated with various groups in the Anatomy Department examining the potential of bone marrow derived mesenchymal stem cells to give rise to neuronal/glial lineages in response to various growth factors and tissue culture manipulations.
Lee had ethical committee approval in Brazil for creating artificial gametes from umbilical cord blood derived stem cells.
[7] Lee originally researched his Ph.D. at UCL under the supervision of Professor Ricardo Miledi FRS in the school of Sir Bernard Katz.
[12][13] Lee changed his focus to embryos, when he realised that many of the questions framed by his Neuroscience research were rooted in the matter of differentiation.
[14][15] Lee became a clinical embryologist in 1985, when working with the gynaecologist Ian Craft[16] he directed the IVF laboratory at the Wellington Hospital in London, then one of the largest units in the world.
Lee also wrote an article in the Sunday Times (10 November 2002) in the aftermath of a number of high-profile embryo transfer mixups in several human IVF clinics.
Professor Sammy Lee arranged a conference co-sponsored by the Progress Educational Trust entitled '21st Century Motherhood' at the University College London (UCL) (18 September 2009).