[4] A spiritual sequel to the 2019 film Dream Girl,[5] the film stars Ayushmann Khurrana, alongside an ensemble supporting cast, including Ananya Panday, Paresh Rawal, Annu Kapoor, Rajpal Yadav, Vijay Raaz, Asrani, Abhishek Banerjee, Manjot Singh and Seema Pahwa.

[6][7] The film is about a man who cross-dresses and disguises as a woman, leading to a lot of chaos and confusion.

[9] Karamveer "Karam" Singh is a young middle-class man living in Mathura and works as a Jagarata performer.

His father Jagjit Singh is in huge debts after borrowing multiple loans and is unable to repay them.

In order to earn quick money, Karam disguises as a woman going by the alias "Pooja" and becomes a dancer at a bar owned by Sona Bhai.

Karam's best friend Smiley Singh Dhillon is in love with Sakina, the daughter of the hostile Abu Saleem.

Smiley requests Karam to pose as "Pooja" and pretend to be a psychiatrist for treating Shah Rukh.

Karam, seeing the opportunity to receive the money, decides to proceed with the wedding, and abscond later.

On the first night after the wedding, Yusuf sees "Pooja" urinating like a man and dies of shock.

As "Pooja" cannot go to the bar to dance regularly anymore, Sona Bhai keeps calling her and asking her to come back to work.

Shah Rukh is shocked and reveals that he is actually gay and Abu forcefully had him break up with his boyfriend so that he can marry a girl instead.

[21] Taran Adarsh of Bollywood Hungama awarded the film 3.5/5 stars and wrote "Dream Girl 2 works due to the plot, extremely funny scenes, commercial treatment, and performances.