[3][4] After signing, Rom made his professional debut with the Rookie-level Gulf Coast League Orioles, posting a 1.76 ERA over 30+2⁄3 innings.
[5] In 2019, he played with the Delmarva Shorebirds of the Single-A South Atlantic League, earning All-Star honors while appearing in 21 games (making 15 starts) and pitching to a 6–3 record, a 2.93 ERA and 122 strikeouts over 95+1⁄3 innings.
[8] Rom began the 2021 season with the Aberdeen IronBirds of the High-A East and was promoted to the Bowie Baysox of the Double-A Northeast in late July.
[18] Rom did not appear in a game for the Orioles during their series against the Tampa Bay Rays, and was optioned down to Triple-A Norfolk on May 11, becoming a phantom ballplayer.
[19] On August 1, 2023, the Orioles traded Rom, César Prieto, and Zack Showalter to the St. Louis Cardinals in exchange for pitcher Jack Flaherty.