Drohiczyn ([drɔˈxʲit͡ʂɨn]) (Lithuanian: Drohičinas/Drogičinas, Belarusian: Дарагічын, romanized: Darahichyn) is a town in Siemiatycze County, Podlaskie Voivodeship, Poland.

Drohiczyn, regarded as one of the oldest towns of the region of Podlasie, was in ancient times located among dense forests.

In 1142, Grand Duke Vsevolod II of Kiev divided his realm between his family, granting Drohiczyn (as Dorohychin) and Brest to his younger brother Igor.

On March 8, 1237, Duke Konrad I of Masovia handed Drohiczyn, together with the area between the Bug and the Narew, to the Order of Dobrzyń.

After a victorious war, the position of Duke Daniel of Galicia grew so strong that he was crowned the King of Ruthenia.

Swedish soldiers, led by Magnus Gabriel De la Gardie appeared in the town in August 1655.

In late 1655, a unit of Crimean Tatars, allied with Poland, appeared in the area of Drohiczyn and spent whole winter here, looting all farms and the town.

On May 3, 1657, a Transilvanian army of George II Rákóczi, which also consisted of Swedes, Cossacks and Wallachians, captured Drohiczyn.

The town suffered during the Great Northern War: hunger was widespread, and the marching armies of Sweden, Saxony, Russia, Poland and Lithuania looted Drohiczyn.

Following the third partition of Poland, Drohiczyn was divided in 1795 between Habsburg Empire and the Kingdom of Prussia, as the new border went along the Bug river.

Furthermore, the Soviet occupants devastated the local church, which was turned into stables, and a Benedictine abbey, which served as a warehouse of building materials.

In November 1939, after a rigged referendum, Drohiczyn was annexed into the Soviet Belarus, and USSR passports were handed to local residents.

This resulted in mass draft of teenagers into the Red Army, also a large group of 14- and 15-year-olds was sent to the heavy industry plants at Omsk; most of them never returned home.

Drohiczyn was quickly captured, and during the German occupation, the town was an important center of the Home Army and other partisan organizations.

Together with the whole Bezirk Bialystok, Drohiczyn belonged to East Prussia, while the General Government was located on the other side of the Bug.

German authorities permitted local Poles to settle in the border area, they also allowed the church to be reopened.