The cathedral is an active parish church with a wide demographic of about 600 families, but also serves an important role in Diocesan life.

The cathedral seeks to serve the community of Dromore by bringing Christ's compassion, love and hope of salvation to people of all ages.

The church was rebuilt numerous times in the 16th and 17th centuries and was made a cathedral by letters patent in 1609, before being destroyed by rebel insurgents in 1641.

In the twelfth century, the English King Henry II revised a system of dioceses and bishops which covered the entire island of Ireland.

A semi-circular sanctuary in memory of Bishop Jeremy Taylor was designed by Thomas Drew FRSA during the ministry of Canon Beresford Knox in 1870.