Forming a parallel street to Vasagatan and Sveavägen, Drottninggatan is intersected by (south to north) Fredsgatan, Jakobsgatan, Herkulesgatan, Vattugatan, Klarabergsgatan, Mäster Samuelsgatan, Bryggargatan, Gamla Brogatan, Kungsgatan, Apelbergsgatan, Olof Palmes Gata, Barnhusgatan, Adolf Fredriks Kyrkogata, Wallingatan, Kammakargatan, Tegnérgatan, Rådmansgatan, Kungstensgatan and Observatoriegatan.
The street was laid out in the 1630s and 1640s when the surrounding area was built on a rectilinear grid plan, a significant innovation in Stockholm's urban environment.
It was originally named Stora Konungsgatan ("Great King's Street") and was later renamed as Drottninggatan in honour of Queen Christina, who ruled from 1632 to 1654.
[4] On 7 April 2017, the street was again the site of another terrorist incident, a deadly truck ramming in which five people died and fifteen more were injured.
[7] Another famous resident was the 19th century banker and newspaper tycoon André Oscar Wallenberg, who lived with his family at Drottninggatan 66 until 1876.