The primary aim of the committee is to review and investigate the scientific evidence of drug harms without the political interference that could result from government affiliation.

Curran and Nutt oversaw research at Imperial College London, in which volunteers took part in a double blind study, taking either 83 mg of MDMA or a placebo before going into the fMRI scanner.

Some participants in the study also appeared on the show, including a vicar, an ex-soldier, writer Lionel Shriver, actor Keith Allen and former Liberal Democrat MP Evan Harris.

Snow, along with fellow journalists Matthew Parris and Jennie Bond, took part in "a groundbreaking trial," consuming cannabis in both skunk and hash form and having their brains imaged with an fMRI.

[30] Throughout the program, Nutt and Drug Science Scientific Committee member, Professor Val Curran, gave expert commentary and interpreted the fMRI results.

This experiment, funded by Channel 4, Drug Science, and the Beckley Foundation was a part of a larger trial at University College London (UCL), examining the effects of cannabis on the brain.

[33] T21 allowed eligible patients to access affordable medical cannabis treatment, with their progress monitored to gather real-world evidence supporting NHS funding for such therapies.

[34] By 2021, Drug Science published its first T21 paper, making findings accessible to the public, and the registry surpassed 1,000 registered patients, a significant milestone for medical cannabis research.

[38] Additionally, Drug Science has studied and published results regarding the usage of CBD-based medicines in controlling symptoms of Long COVID.

This collaboration seeks to address concerns that the 'psychotherapy' aspect of MDMA-assisted psychotherapy—which expert opinion considers crucial to long-term success involving MDMA as a psychotherapeutic agent—is not yet well understood and may be suboptimal.