Du Bois is a village in Washington County, Illinois, United States.

[5] In 1869, the village was renamed for Jesse K. Du Bois, state auditor of public accounts, 1856-1864.

[7] According to the 2010 census, Du Bois has a total area of 1.07 square miles (2.77 km2), all land.

38.5% of all households were made up of individuals, and 22.9% had someone living alone who was 65 years of age or older.

About 17.3% of families and 15.7% of the population were below the poverty line, including 15.7% of those under the age of eighteen and 27.8% of those 65 or over.