By the peak of the California Gold Rush in the 1850s, Dublin had established itself as a significant crossroads city in the San Francisco Bay Area.

Given the school's Irish place name, Hagler had suggested that the mascot (the Gael) and colors (red and blue) of nearby Saint Mary's College of California might be an appropriate starting point for the discussions, and the committee eventually agreed with Hagler's idea, while adding white to the colors.

[3] By 2015, the Dublin Unified School District outlined a second comprehensive high school as one of its top priorities—as listed in its Facilities Master Plan[7]—citing a survey showing Dublin High faculty members' desires for additional classrooms and renovations of old facilities.

In the meantime, 2017 saw a beginning of protest and outcry from Dublin High teachers, who had struggled with increased class sizes without proper staffing accommodation or financial compensation.

[10] As negotiations for appropriate pay raises and contractual improvements stagnated for months, members and supporters of the Dublin Teachers Association (DTA) took to the streets in a candlelight march to the District office, culminating in a series of statements at the ongoing School Board meeting.

In March 2019, the DTA threatened to go on strike if negotiations remained stagnant; a tentative agreement including a pay raise and class size limitation was reached in April.

[13] The academy starts accepting students at the end of 8th grade; selective interviews are held to determine placement.

The academy is closely affiliated with the school's HOSA club and offers a mentorship program in the eleventh grade to further career development.

[15] This exclusive academy allows students to network with industry professionals and get priority to take a variety of engineering classes.

In 2021, a three-floor Science and Engineering finished construction, allowing for expansion of the academy as well as general classes.

The Irish Guard has performed at field show competitions, home football and basketball games, concerts, and community events.

Dublin High also hosts an active Drama department, which offers courses and clubs that culminate in fall plays, spring musicals, student-directed One Acts, and attendance at the annual Lenaea High School Theatre Festival in Folsom, California.

Presenting scholarship opportunities, processing work permits, and hosting guest speaker events.

In 2019, Dublin High opened its Wellness Center in to cater to students' emotional needs and bring awareness to mental health.

[24] On February 22, 2012, MythBusters stars Adam Savage and Kari Byron participated in a panel session at the Dublin High School Engineering and Design Academy Open House.