Duchess Hedwig of Württemberg (15 January 1547, Basel – 4 March 1590, Marburg) was a princess of Württemberg by birth, and by marriage Landgravine of Hesse-Marburg.

Hedwig was the eldest daughter of the Duke Christopher of Württemberg (1515–1568) from his marriage to Anna Maria (1526–1589), daughter of the Margrave George of Brandenburg-Ansbach-Kulmbach.

She married on 10 May 1563 in Stuttgart Landgrave Louis IV of Hesse-Marburg (1537–1604).

As a result, he remained with the Duke of Württemberg in close religious association, but he also came into confrontation with his brother William, who wanted to unite all Protestant forces in Germany.

Hedwig died on 4 March 1590 and was buried next to her husband under in a tomb, with her statue in the St. Mary's Church in Marburg.