In 1424, after Bolko V the Hussite became the independent ruler over Głogówek and Prudnik thanks to the resignation of both his father and uncle Bernard.

However, almost immediately, the young Duke, at that time in Gliwice, not only decided to admit the Hussites into his city in order to avoid the destruction of his duchy, but also took the occasion to enrich himself with the secularization of the local churches (one of his first decisions was the cancellation of the building of a Kolegiata in Głogówek, which began by orders of Bolko IV).

One aim of the duke was the policy of a gradual Germanization of Silesia, and the national teachings of Jan Hus fit in with this purpose.

In 1429 with the Hussites involved on other fronts, Bolko V acquired for himself the neighboring Duchy of Nysa, which belonged to the Bishopric of Wrocław.

In the following year, together with his allies, he forced Polish troops to retreat to Jasna Góra, which become the new Silesian-Poland frontier.