Dudhmukhi Wildlife Sanctuary (Bengali: দুধমুখী বন্যপ্রাণ অভয়ারণ্য) is a wildlife sanctuary located near Sarankhola in Bagerhat District of Bangladesh.

The area of the sanctuary is 170 ha (420 acres).

It was officially declared as a wildlife sanctuary by the government of Bangladesh on 29 January 2012.

[1] It is one of the safe zones for vultures as per the Vulture Safe Zone-2 Schedule of the government of Bangladesh in 2012.

[2] Most of the area of Dudhmukhi consists of wetlands[3] and Dudhmukhi river is one of the dolphin sanctuaries in Bangladesh.