Duff's Famous Wings is a restaurant based in the Amherst suburb of Buffalo, New York.

The restaurant was established in 1946 under the name "Duff's", referencing its founder, Louise Duffney.

[1] In 1985, the restaurant was renamed "Duff's Famous Wings" after Buffalo wings became its major selling point.

[1] Duff's Famous Wings is known throughout Western New York as having good chicken wings[2][3][4] and is noted for its rivalry with the Anchor Bar, the bar credited with inventing the Buffalo wing.

In 2014, Duff's partnered with the Buffalo Bills to announce that a version of Duff's Famous Wings was added to Ralph Wilson Stadium.