It was created in the first half of the 14th century for the eldest son of Robert of France, Count of Clermont, and Beatrice of Burgundy, heiress of the lordship of Bourbon.

Although the senior line came to an end in 1527, the cadet branch of La Marche-Vendome would later succeed to the French throne as the Royal House of Bourbon, which would later spread out to other kingdoms and duchies in Europe.

Peter II and his wife, Anne, daughter of Louis XI, had only one surviving child, Suzanne.

Suzanne died childless, and the new king's mother, Louise of Savoy, claimed her inheritance, as heir by proximity of blood.

In 1523, Louise of Savoy, mother of King Francis I of France, challenged the succession to the estate of Suzanne, Duchess of Bourbon, who died childless.

She claimed the succession as the heir by proximity of blood, as a descendant of the House of Bourbon through her mother.

Seeing no hope of prevailing against the king's mother, the Constable of Bourbon went into the service of Charles V, Holy Roman Emperor.

The title was vacant til 1544 and then created for Charles II de Valois, the youngest and third son of King François I of France and Claude, Duchess of Brittany.