[2] The village was established in the 17th century[3] by Pontic Greeks who fled the coast of Pontus in order to escape the oppression of the Derebeys.

[4] It was originally named Santa (Σάντα) and was an important caravan and mining village, with 13 neighborhoods and more than 5,000 citizens.

Pontian guerrilla bands appeared in the mountains of Santa as early as 1916 under the leadership of Euklidis Kourtidis and successfully resisted a Turkish attack on September 6, 1921.

[4] After the exchange, the village was completely vacated and renamed and the lands and properties were registered in the Turkish treasury.

The town of Nea Santa was founded by them in the Kilkis regional unit in Central Macedonia.