The KwaZulu-Natal Division of the High Court of South Africa is a superior court of law with general jurisdiction over the KwaZulu-Natal province of South Africa.

As of January 2024[update] the Judge President of the division is Thoba Poyo-Dlwati.

The Natalia Republic, established in 1839 by Voortrekkers, was annexed by Britain in 1843 and renamed Natal.

In 1844 it was attached to the Cape Colony, and in 1846 a District Court for Natal was established with its seat in Pietermaritzburg.

After former South African President Jacob Zuma failed to appear in court on 4 February 2020, the KwaZulu-Natal Division of the High Court of South Africa issued an arrest warrant against Zuma.