In February 2006, the Government of Tajikistan began demolition of the Jewish community compound as part of an urban redevelopment plan designed to make way for a new presidential residence, the Palace of the Nation, with adjoining landscaped areas.

The demolition of the synagogue was delayed due to international protests and a series of court actions until the end of June 2008, when the old building was finally razed.

Demolition, originally scheduled for 2004, began in early February 2006 with the destruction of the community's mikvah, or ritual bath, kosher butcher, and classrooms.

[1][2] The government ordered the demolition of the entire Jewish community compound, including the synagogue, in accordance with city center regeneration plans, specifically the construction of the Palace of the Nation surrounded by extensive landscaped grounds.

[8] In March 2006 it appeared for a short time that the Government of Tajikistan had reversed their decision and would allow the Jewish community to keep the synagogue on the current site.

[11] Although the government refuses to compensate the Jewish community for the loss of the building, it has allocated a plot of 1,500 square meters for the construction of a new synagogue on the banks of the Dushanbinka River in the Firdavsi municipal district in the west of the city.

The New Dushanbe Synagogue was opened on 4 May 2009 in an existing building donated for this purpose by Hasan Assadullozoda, a Tajik businessman and the brother-in-law of President Emomalii Rakhmon.