[1][2] Tokarski led the Spokane Chiefs of the Western Hockey League (WHL) to the 2008 Memorial Cup and was named the top goaltender and most valuable player of the tournament.

He has won the American Hockey League's (AHL) Calder Cup twice: first with the Norfolk Admirals in 2012, and then with the Charlotte Checkers in 2019.

Tokarski made 53 saves in the final as Spokane defeated the Ontario Hockey League (OHL)'s Kitchener Rangers to claim the Chiefs' second Memorial Cup championship in franchise history.

He made his NHL debut on January 19, 2010, against the New York Rangers, replacing Antero Niittymäki in the third period after the latter had surrendered six goals.

In Game 3, Tokarski made 35 saves on 37 shots to help the Canadiens win 3–2 in overtime, cutting the Rangers' series lead to 2–1.

[13] Following the conclusion of the Canadiens' 2014–15 pre-season, goaltender Peter Budaj was traded to the Winnipeg Jets on October 6, 2014, effectively leaving Tokarski as Carey Price's backup for the 2014–15 season.

[14] At the beginning of the 2015–16 season, on October 5, 2015, Tokarski was placed on waivers, ending his tenure as backup goaltender for the NHL club.

[17] His lone appearance for the Ducks came on October 28, 2016, where he stopped all five shots faced in relief during a 4–0 loss to the Columbus Blue Jackets.

[22] On November 4, 2020, Tokarski joined his sixth NHL organization, signing as a free agent to a two-year, two-way contract with the Buffalo Sabres.

[28] In the 2023–24 season, Tokarski was assigned to the AHL for the duration of his contract with the Sabres, posting 11 wins through 24 appearances for the Rochester Americans.

[30] Following 5 appearances with the Wolves, Tokarski was signed to a one-year, two-way contract to add depth to NHL affiliate the Carolina Hurricanes on December 2, 2024.

[31] Tokarski made his debut for the Hurricanes on December 15, 2024 versus the Columbus Blue Jackets in Raleigh, earning a win after making 27 saves against 28 shots.

[33] Tokarski played his best game in the final, posting 39 saves on 40 shots as Canada defeated Sweden 5–1 to win its fifth consecutive gold medal.