The Dutch contributed a monumental work called Hortus Indicus Malabaricus on the medicinal properties of Malabar plants.
Cochin and the chief of Paliyam provided supplies to the Dutch, who faced heroic Portuguese resistance during the prolonged siege.
Though disrupted by monsoon rains and the deaths of the ruler of Calicut and important Dutch officers, the garrison finally capitulated on 8 January 1663.
The Dutch authorities in Amsterdam were alarmed and wrote to their officers in India to "spare no pains" to secure the expulsion of the British from Calicut.
After a year of desultory fighting, the Calicut forces withdrew, and the Dutch destroyed the Fort Round and built a bastion near Cranganore.
Thirty Dutch lost their lives this raid, and in the confusion of the battle, the Royal Sword of Calicut was destroyed.
The Commissary General of Batavia, the head of the Dutch Government in the East Indies, came to Ponani in 1696 without even stopping at Cochin.
In 1721, the supreme council of the Dutch East Indies in Batavia agreed that it would no longer support its ally Cochin against Calicut, betraying century old friendship.
The Dutch never succeeded in establishing a pepper trade monopoly in Malabar and were all the more frustrated in their attempts when the young ruler of Travancore, Marthanda Varma, started to expand his kingdom.
De Lannoy later helped Travancore to establish an organized army, introduce better firearms and artillery, and to build European style forts in his state.
As a result of the Kew Letters, Dutch settlements on the Malabar Coast were surrendered to the British in 1795, in order to prevent them from being overrun by the French.
They relied heavily for trade and diplomatic missions on the Paradesi Jewish merchants of Cochin, who thrived during the Dutch era.
The Murugan temple at Thiruchendur was occupied by the Dutch East India company between the years 1646 to 1648, during the course of their war with the Portuguese.