In 2006, the main portion of the mall was demolished and replaced with a Home Depot except for the Jamesway and Service Merchandise anchor store buildings.

[5] Other included Flah's, a local department store, a pharmacy named Drug World, as well as Radio Shack and Waldenbooks.

With both anchor stores gone, the other shops began ending operations as well, and by 2001 only the flea market remained, with the rest of the mall sealed off entirely.

[8] In 1999, plans were announced to convert the mall into a business community named Hudson Valley Metro Centre.

In 2003, a group of designers from New York devised a plan to convert Dutchess Mall into a women's prison.

[11] The main section of the mall was eventually demolished and replaced with a Home Depot, which opened on July 5, 2006.

It is not connected to the May Company.As of 2024, besides the Home Depot, and the DCC campus, there is also a McDonald's and a Citizen's Bank branch occupying space toward the front of the property.