[1] It introduced the Bechdel test, a set of criteria for determining gender bias in works of entertainment, that has since found broad application.

On May 10, 2008, Bechdel announced that she was putting the strip on indefinite hiatus in order to complete her graphic novel memoir Love Life,[4] which was eventually published in 2012 as Are You My Mother?.

[10] In 2023, forty years after the strip's debut, DTWOF was adapted as a streaming podcast series on Audible by playwright Madeleine George and featured the voices of Carrie Brownstein, Roberta Colindrez, Roxane Gay, Jenn Colella and Jane Lynch, with Bechdel's approval.

When Ginger wanted to move on, the group was able to buy her share by Sparrow taking the Executive Director position at the state NARAL office.

[13] Only some of the characters' surnames were known, since such names appeared only when it was appropriate to the dialogue (when Ginger and Sydney, as college instructors, were addressed as "Professor Jordan" and "Dr. Krukowski", for instance) and were not established from the beginning.

Sydney also drinks Loch Lomond, a brand of Scotch whisky famously invented by Hergé in The Adventures of Tintin.