Dylan McDuffie (born February 19, 2000)[1] is an American football running back for the Kansas Jayhawks of the Big 12 Conference.

He transferred to Saint Francis High School in Athol Springs, New York for his junior season before returning to Sweet Home for his senior year.

[2] He played both running back on offense and linebacker on defense in high school, earning all-star recognition at each position.

[3] In 2016, as a junior, he earned All-Western New York Second Team honors after accumulating 1,255 rushing yards, 25 receptions, 290 receiving yards, 14 rushing touchdowns, and three receiving touchdowns as he led Saint Francis to the Monsignor Martin final.

[2][4] Further, he was a 2016 Connolly Cup finalist (which was won by his cousin) and also named Western New York's best high school football player by the Riverside Athletic Club.

With a defensive performance that included 73 tackles, he earned a 2017 All-Western New York Honorable Mention selection as a linebacker.

In 2018, as a true freshman, he appeared in four games, recording 14 carries for 70 yards in a reserve role behind Patterson.

[18] However, on January 31, 2022, after considering offers from California, Oregon, and Oklahoma, he withdrew his name from the transfer portal, and will return to Buffalo for his redshirt senior 2022 season as the team's starting running back.

In week 6, McDuffie would rush for a season high 91 yards on 13 carries and two touchdowns against Central Florida.

[27] In December 2021, he hosted a holiday toy drive, in conjunction with the Boys and Girls Club of Buffalo, to benefit local children and families.