Endeley was born in Buea then under the Colony of German Kamerun until administrative control was divided between the French and British after the Treaty of Versailles was signed.

[2] Endeley was concerned with providing a voice for workers in British Southern Cameroons and for citizens of that territory in general.

As a medical student in 1939, he helped form the Cameroon Youth League (CYL) in Lagos and became its General Secretary.

In 1946, after the United Nation's approved a British trusteeship for Eastern Cameroon, a development corporation was established to stimulate growth in agricultural produce.

Endeley allied the KNC with the Kamerun People's Party (KPP), another pro-Nigeria group, but the coalition lost seats to the KNDP.

In May 1960, his KNC merged with the KPP to form the Cameroon People's National Convention (CPNC) to be the main opposition party to Foncha's KNDP.

Political opinion was strongly in favour of reunification with French Cameroun, and the United Nations held a plebiscite over the issue on 11 February 1961.

He served as a member of the Cameroon National Union's central committee, and in 1966, he became president of the Fako section, a post he held until 1985.