[2] This was title was followed with the most devastating event in the club history, as San Pablo were unable to defeat El Vencedor (who were the 2018 Apertura Champion) in a promotion playoff 6–5 after penalties, after tying 0–0.

On June 29, 2024 EF San Pablo Tacachico announced on the team social media platform that due to several sponsors pulling support, high team cost and lack of fans support, the club announced they would be withdrawing from the Segunda Division.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.