The fourteenth season of the American fictional drama television series ER first aired on September 27, 2007, and concluded on May 15, 2008.

The season was executive produced by Christopher Chulack, Michael Crichton, John Wells, David Zabel, Joe Sachs, and Janine Sherman Barrois.

Chulack served as a regular director along with his production role and contributed four episodes including the series finale.

Long serving series directors Richard Thorpe and Félix Enríquez Alcalá each contribute a single episode this season.

Former cast members Laura Innes and Paul McCrane continue to direct for the series, each contributing a single episode this season.

After being passed over for Chief of the ER, Pratt considers taking a position elsewhere, but reconsiders after working with Jeanie Boulet.

She comes in after her son, Carlos, is admitted from an apparent head injury, and he is found to have a brain lesion — possibly a sign of AIDS.