In 1988, ES Sétif won the African Cup of Champions Clubs by beating Iwuanyanwu Nationale of Nigeria 4–1 on aggregate in the final.

[9] On August 8, 2010, ES Sétif defeated CS Sfaxien of Tunisia 1–0 to win the first-ever edition of the UNAF Super Cup.

[10] ES Sétif whose team has regularly taken part in Confederation of African Football (CAF) competitions.

Qualification for Algerian clubs is determined by a team's performance in its domestic league and cup competitions, ES Sétif have regularly qualified for the primary African competition, the African Cup, by winning the Ligue Professionnelle 1.

After six years of absence, ES Setif returned to continental competitions, this time in the African Cup of Champions Clubs, for the first time The following year and in the same competition, despite falling to the second division, Les Aigles Noirs managed to achieve the title for the first time against Iwuanyanwu Nationale of Nigeria and after the defeat in the First leg 1–0, they achieved an overwhelming victory in the Second leg 4–0 in a match that took place at Stade du 17 Juin in Constantine, After that, they met with Al Sadd SC in the final of the Afro-Asian Club Championship, and won the title for the first time, which is the only one of its kind in the history of Algerian football.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Below are the notable former players who have represented ES Sétif in league and international competition since the club's foundation in 1958.