[9] The East Bengal Women's team started off their campaign in the 2020 Kanyashree Cup in style as they defeated Dipti Sangha by 6–1.

On 30 December 2020, East Bengal faced SSB Women's at the Salt Lake Stadium in the final of the Kanyashree Cup and finished runners up with a 2–0 loss, with a goal conceded in each half.

[13] However, due to a tussle between the club officials and the investor group Shree Cement, the women's football team and all the players were released.

[17][18] East Bengal started their campaign with a 2–0 win against WB Police on 20 December at the Rabindra Sarobar Stadium, with Sulanjana Raul and Kabita Saren scoring for the team.

[19] On 10 January 2023, in their fourth match of the season, East Bengal defeated Behala Aikya Sammilani by 35–0, creating a record as the biggest win by an Indian team in any women's football game conducted by AIFF.

[21] On 19 January, East Bengal defeated Adivasi United Students Club 3–0 in the last match of the group stages to enter the knockouts.

They finished top of the group with seven wins, including two walkovers given by Dipti Sangha and Kolkata Union Sporting Club, having scored fifty-eight goals without conceding a single.

[23][24] On 23 January, East Bengal faced New Alipore Suruchi Sangha in the quarter-finals and won 2–1 with goals from Mousumi Murmu and Sulanjana Raul.

[32][33] On 22 April, the club announced the squad for the Indian Women's League campaign, with eleven names from the Kanyashree Cup championship team.

[37][38][39][40] On 2 May, East Bengal registered their second win as they defeated Mata Rakmani FC 2–0 with goals from Mousumi Murmu and Rimpa Haldar.

[42] On 12 May, East Bengal defeated HOPS 1–0 in the last match of the group stage courtesy of a solitary strike from captain Ratna Halder as they secured a top four finish and ensured a place in the knockouts in their maiden appearance and also earned an automatic qualification for the 2023–24 Indian Women's League.

East Bengal also roped in the two time IWL winning coach Anthony Andrews from Gokulam Kerala by paying a record transfer fee in women's football in India.