East Cape Girardeau is a village in Alexander County, Illinois, United States.

[3] It is part of the Cape Girardeau–Jackson, MO-IL Metropolitan Statistical Area.

A post office was established at East Cape Girardeau in 1874, and remained in operation until 1913.

[4] The village lies east of Cape Girardeau, Missouri, hence the name.

33.33% of all households were made up of individuals, and 21.57% had someone living alone who was 65 years of age or older.