East Home Avenue Historic District is a national historic district located at Hartsville, Darlington County, South Carolina.

Home Avenue has historically been the major residential street in Hartsville since it was laid out and landscaped in 1890.

Located in the district is the separately listed John L. Hart House.

[2][3] It was listed on the National Register of Historic Places in 1991.

This article about a property in Darlington County, South Carolina on the National Register of Historic Places is a stub.