It encompasses part of an area that was, before the 1813 construction of the Boston Manufacturing Company further west, developing as a center of the community.

Because of the company's economic influence, the center was more fully developed further west, and East Main Street became a fashionable area for upper class housing.

Built c. 1900, it is a Colonial Revival structure with significant Queen Anne and Shingle style elements.

The Francis Blanchard House, at 428 Main Street, was built c. 1850-54, and has Greek Revival features, including a pedimented gable end facing the street and corner pilasters, but it also has a typically Italianate round-arch window in the gable.

The George W. Chamberlain House at 418 Main Street (built about the same time) is more strongly Italianate, with a projecting gable roof that has paired brackets and a crowning belvedere.