The East Orange VA Medical Center is a United States Department of Veterans Affairs hospital complex located at 385 Tremont Avenue in East Orange of Essex County, New Jersey.

[5] Listed as the East Orange VA Hospital, it was added to the National Register of Historic Places on September 4, 2018, for its significance in health/medicine.

[6] After World War II, the Veterans Administration built new medical facilities near urban areas.

[6] The East Orange VA Hospital is a 34-acre (14 ha) historic district encompassing the medical center campus.

It was listed as part of the United States Third Generation Veterans Hospitals, 1946–1958, Multiple Property Submission (MPS).