East Thermopolis is a town in Hot Springs County, Wyoming, United States.

According to the United States Census Bureau, the town has a total area of 0.18 square miles (0.47 km2), all land.

60.5% of all households were made up of individuals, and 42.1% had someone living alone who was 65 years of age or older.

56.0% of all households were made up of individuals, and 38.7% had someone living alone who was 65 years of age or older.

About 7.0% of families and 16.8% of the population were below the poverty line, including 9.8% of those under the age of eighteen and 22.4% of those 65 or over.

Public education in the town of East Thermopolis is provided by Hot Springs County School District #1.