East Tyrone was a constituency of the Parliament of Northern Ireland.

It was created in 1929, when the House of Commons (Method of Voting and Redistribution of Seats) Act (Northern Ireland) 1929 introduced first-past-the-post elections throughout Northern Ireland.

Mid Tyrone and West Tyrone were strongly nationalist, while the constituencies covering the north and south of the county were consistently won by unionists.

East Tyrone was marginal between the two traditions, with nationalists just outnumbering unionists.

The Northern Ireland Parliament was prorogued in 1972 and formally abolished in 1973.