The Eastern Illinois Panthers men's soccer team represents Eastern Illinois University (EIU) as a member of the Ohio Valley Conference in NCAA Division I soccer.

[2] The Panthers play their home matches at Lakeside Soccer Field located directly south of the Lantz Arena complex on the EIU campus in Charleston, Illinois.

[3] Eastern Illinois is currently a full member of the Ohio Valley Conference (OVC), which did not sponsor men's soccer until the 2023 season.

Upon joining the OVC, EIU also became an affiliate member of the Missouri Valley Conference (MVC) for men's soccer.

In March 2023, the OVC announced that it would start a men's soccer league in the 2023 season, allowing EIU to align men's soccer with the bulk of its other sports,[4] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.