[6][7] In September, she played for Melbourne in the women's all-star exhibition match at VU Whitten Oval.

[9] Marinoff made her debut in the club's inaugural match in round 1, 2017 against Greater Western Sydney at Thebarton Oval, where she gathered a game-high twenty disposals and six tackles in the 36-point win.

[11] Marinoff was a member of the Adelaide team that won the inaugural AFL Women's premiership in 2017, defeating Brisbane by six points at Metricon Stadium.

[15] After an impressive start to the 2018 season, in round 4, Marinoff set a new record for tackles with 21 in her side's draw against Greater Western Sydney in heavy rain at Blacktown ISP Oval,[16] breaking the record of 16 set by Carlton midfielder Sarah Hosking two weeks earlier.

[18] Marinoff was selected in afl.com.au's Team of the Week in rounds 3,[19] 4,[20] 5[21] and 7,[22] and finished equal-fifth in the 2018 AFL Women's best and fairest count with six votes.

[37] Marinoff finished the home-and-away season equal with North Melbourne's Ashleigh Riddell in first for kicks (94) and average kicks per game (15.7), also improving her career-best average in disposals per game (23.2), and was one of fourteen players to have played the most AFL Women's matches to that point with 30.

[45] During a practice match in the 2021 pre-season, Marinoff made front-on contact with Greater Western Sydney player Bríd Stack in an incident that saw Stack suffer a fractured vertebra and was given a three-match suspension, the longest suspension in the competition's history to that point.

[52][53][54] After leading the competition in total and average kicks during the 2021 season, Marinoff was named in the 2021 AFL Women's All-Australian team[57][58] and won her first Adelaide Club Champion award.

[61][62] Marinoff was also selected in Champion Data's 2021 AFLW All-Star stats team, after placing in the top ten for every midfield statistical category.

[89] She was named in Champion Data's 2022 season 6 AFLW All-Star stats team after leading the competition for metres gained with 395.7 a game.

[94] Despite Adelaide finishing first on the home-and-away ladder, they exited the premiership race in the preliminary finals for the second consecutive year.

[96] Leading into the 2024 season, Marinoff and Sarah Allan were announced as Adelaide's new co-captains, replacing Chelsea Randall.

[97] In week 1, Marinoff won the Showdown Medal for best afield in the Showdown against Port Adelaide with 29 disposals and nine tackles,[98] polling nine coaches' votes,[99] and was among Adelaide's best players in its win over Fremantle in week 2,[100] polling nine coaches' votes.

[109] Marinoff was again Adelaide's best player in its week 7 loss to Melbourne with 29 disposals and 17 tackles, becoming the first AFLW player to record 2,000 career disposals,[110] and was best afield in its week 7 win over Greater Western Sydney with a career-high 41 disposals and 17 tackles;[111] Marinoff's 19 votes across Adelaide's week 7 matches saw her lead the voting for the AFLCA AFLW champion player of the year award after the compressed period of the season,[112] having averaged career-highs in disposals (31), clearances (6.8) and tackles (12.9) to that point,[113] and she would go on to win the award with 91 votes, ahead of three-time winner Jasmine Garner on 79 votes.