She had a supporting role in the 2018 drama film If Beale Street Could Talk and the following year began starring as Karen Mott in the BET comedy-drama series, Sistas.

[6] The series started as a micro budget project that eventually attracted more than 45,000 unique viewers with over 1 million channel views.

Later in 2019, she began starring as Karen Mott, one of lead characters, in the BET comedy-drama series, Sistas by Tyler Perry.

[14] In 2023, Obsidian was cast opposite Kerry Washington, Susan Sarandon and Oprah Winfrey in the war drama film, The Six Triple Eight.

[18][19][20] Ian Thomas wrote in review for website Black History Month: "Ebony Obsidian shines as Lena Derriecott King, a battalion member whose personal journey reflects the broader struggles and triumphs of the unit.