Edward Chalupka (February 23, 1947 – November 17, 2019) was a Canadian Football League (CFL) player.

He played college football at the University of North Carolina.

[1] Chalupka played his entire professional career as a guard for the Hamilton Tiger-Cats, from 1970 through 1976.

In 1981, five years after retiring from the CFL, Chalupka was elected as the fifth president of the Canadian Football League Players' Association (CFLPA).

He served as CFLPA president until 1986, and was succeeded and preceded in that role by Saskatchewan Roughriders running back George Reed.