He was a reporter for the morning show RI:SE, and eventually became host of the UK version of Fear Factor.

After months of surgery and therapy, he returned to the show in the Westbrook family episode in Oklahoma from season 4.

During the summer of 2007, Sanders hosted the six-episode run of National Bingo Night on ABC.

On 15 August 2013, AMC debuted the new reality show Owner's Manual hosted by Ed Sanders and Marcus Hunt.

[3] The company name is a play on the slang terms "Limey" due to Sanders being British, and "Yank" as Honea is from the U.S. Sanders's wife, Gioia (née Gagliano), an Italian-American magazine and fashion-show make-up artist, gave birth to triplet daughters on May 5, 2007, in Santa Monica, California.